Thursday 8 June 2023

Make Study Notes on Meiosis and Mitosis

 I gave you a booklet which illustrates mitosis and meiosis.  Please do the following to review the steps.

First, watch the mitosis and meiosis sections of my lesson video. Watch from 5 min and 50 seconds! 

1. Next, WRITE what happens in each step in PEN.   10 marks

2. DRAW the spindlefibres and the centrioles in the correct spot  in each step.10 marks

3. COLOUR the strands of DNA and make the colours consistent throughout the booklet. 10 marks

4. LABEL the section on nondisjunction.  5 marks

5. On the last page, DRAW and label the following on the LAST PAGE 5 marks

a. Chromatin

b. chromatid

c. sister chromatids

d. Chromosome

e. Homologous chromosomes 

EVALUATION

18-20. You completed everything in the questions above and it is in PEN, neatly done, clear and colour coded. You used pen, or you typed it up and printed it, pasting the paper on your sheet.

15-17 You completed everything but it is difficult to read what you did, it is in pencil

5-10  It is a good start but not complete

Wednesday 7 June 2023

An introduction to Genetics

 Watch the introduction to Genetics video and make notes on it. You may use the notes organizer I provided in class called "The analogy of shoes". Please make a correction on the student notes.  Where it says "boy" cross it out and put XY .  Where it says girl, cross that out and put XX.  These are chromosomes for individuals. Note that XY individuals have testes which produce sperm and XX individuals have ovaries which produce eggs.  

The term "boy" and "girl" refers to gender identity and this identity can be for an individual who has XX or XY chromosomes.  


Friday 26 May 2023

Create a presentation on vaccine preventable illnesses

Read about these illnesses on BCCDC, CDC USA,  NHS or BC Health Guide for Q 1-5. For Q 6, see resources below.  Create a powerpoint to present to the whole class.  Make sure each member of your group has a chance to present.  60 marks

1. What is the illness? What are the symptoms? Find photos of symptoms.
2. What pathogen is the cause?  How do you get it? 
3. Can the pathogen hide in your body after you get infected? How? 
4. What is the treatment?
5. What vaccine is recommended?  Most vaccines are given preexposure. Can a vaccine be given after exposure, as treatment? 
6.   Read about a recent case, outbreak or recent research. Summarize findings  

Resources for Q6
1. Shingles linked to dementia  : https://www.nature.com/articles/s41380-021-01138-6
increase in shingles or HZ due to covid 
6. Meningitis ACWY AND Meningitis B 

Monday 15 May 2023

Fetal Circulation

 

 Click on the picture below to play the video 
 

Today we explored fetal circulation.  First we drew our conception of how fetal circulation might occur. Next we compared fetal and baby circulation in depth in the table below.  Finally we drew a schematic diagram to compare the two and listened to a baby cry because the newborn's first breath is when the ductus arterioles and the foramen ovale closes successfully

   



Wednesday 10 May 2023

The Heartbeat, the first sound you ever heard

You have some fill in notes



click on the video below to observe a beating heart

The next video gives a simple and  clear explanation of the chambers, valves and heart sounds


Thursday 4 May 2023

Blood Pressure

 The Major Blood Vessels. DIAGRAM


OK so, during class,  we'll play doctor and find blood pressure.  Have  a look at this tutorial before you test this on each other...


Today you will find blood pressure of the person beside you (participation mark 10)

Lab on Plasma, Lymph, Formed Elements

 Here is some reading on plasma and lymph  link here 

And     NOTES on formed elements 
Here are notes on arteries and veins 


Observe the microscope slides on blood.  For the human samples, 
1.  DRAW THE SPECIMEN. Use a petri dish to draw the circle. 
2.  Label and identify the FORMED ELEMENTS  that you can see such as RBC, WBC, platelets
3.  summarize some information on your specimen using the notes as a guide.  Write these in point form.  Conclusion:  
In a few sentences, identify some of the similarities and differences between human blood and the other mammals such as cat, and rat.  Identify how human blood is different from that of  frog and chicken.   

SPECIMENS:

1.  Artery, vein, nerve of a mammal
2.  Human blood
3. Bird blood or Chicken blood.  Label the RBC and nuclei
4.  Snake blood or  Frog blood
5. .  Human blood: sickle cell anemia 
6.  Rat blood
7.  Cat blood  
8.  Human blood Sickle Cell Anemia 
9.  Human blood: Trypanosoma. (Sleeping sickness)
10 Human blood: Plasmodium vivax (Malaria) 


45-50 All specimens are carefully drawn and labeled. Extensive notes are written beside the observations.  Your work is in colour and brilliantly done

30-44. All specimens are beautifully labeled.   Notes are written beside the observations. 

25  This is incomplete







PATH OF BLOOD AS A SUBWAY MAP

 


THE LONDON TUBE MAP





















We will use A HUGE map of the circulatory system to represents a subway with stations.  The stations are the lungs, heart, legs, head, intestines, liver, kidneys and all the arteries and veins that connect them.  We will model the passengers entering and leaving this subway today. 
 
REVIEW THE NOTES on the path of blood
Pieces of lego two kinds to be cars on the subway
Hemoglobin car
Plasma car

These are the passengers : 
Oxygen
Carbon dioxide
HCO-,  H+
Waste
Nutrients 
Now everyone take a hemoglobin car and start at the lung, oxygen hops on at the lung.  Follow it to the heart aorta and lets go to legs where oxygen gets off and carbon dioxide hops on. 
Put a plasma car on and pick up carbon dioxide too.  Now travel back to heart then lungs, CO2 gets off and oxygen gets on…
Model the rest of the passengers going through the entire system.  Remember that
Oxygen and CO2 can ride on hemoglobin car and everyone but oxygen rides on the plasma car


Here is some reading on Plasma and lymph. another link here 
And     NOTES on formed elements  Have a look and make notes

Assignment 

Create a subway map of the Human Circulatory System which includes
all the major destinations.

1.  indicate arteries and veins as different lines.  Show the direction of the line using arrows. 60 marks
2.  Stations are different areas of the body (Head,  arms, Feet, Liver, Intestine...) and the Heart should be four stations ( left and right ventricle: left and right atrium).  10 marks you mention all stations and none are missing
3.  The map is neat and colourful, inked and it  looks great 60 marks
         55--60 marks - it is easy to read, colourful and inked and extraordinarily creative.
      50 marks - It's impressive!  It's neat, clean and very well done
     45 marks - it is coloured and inked and complete
   0-30 marks- good start, but you probably needed more time








Tuesday 25 April 2023

David Hardwick Pathology Museum

 LOCATION: DHPLC PATHOLOGY MUSEUM AT VGH to learn about human pathologies

DATE: April 28 2023 


We will be going to the following location.  Please meet OUTSIDE  the building beside the starbucks
at 845AM for attendance.  Our program will be in rm 2201 and last until about 11am.  Then you will be dismissed to take the bus back to school.

This is a medical facility and there are vulnerable patients who may be immunocompromised. We will wear masks to protect our community members. 

Create a Field Study Safety plan which includes your group members, contact numbers, emergency contact, itinerary and map. Hand this in.

David Hardwick Pathology Learning Centre
Gordon and Leslie Diamond 
Health Care Centre
2201-2775 Laurel St
Vancouver, BC V5Z 1M9

















CIRCULATION

 Today we will introduce you to the Circulation System.


This is the slideshow

You will receive a gigantic DIAGRAM on circulation

and we will explore the  path of blood . In particular, we will replicate William Harvey's experiment

Read the Summary notes on circulation:
Circulation System
  Major Blood Vessels
  Lymphatic System

Do the review on blood vessels

Thursday 20 April 2023

RESPIRATION

 




The picture link below shows a journey through the respiratory system



Notes are here and please get the diagram notes from me. Plus detailed notes here
Control of respiration
CO2 and H+ Levels
As monitored by the carotid and aortic bodies.  If these levels increase, they send a message to the  medulla oblongata Carotid bodies send the message through VAGUS NERVE.  Aortic bodies send the message through the GLOSSOPHARYNGEAL NERVE.  Medulla oblongata stimulates the rib cage and the diaphragm to move faster.

Acidosis:  pH < 7.35         too much carbon dioxide
Alkadosis: pHB> 7.45       not enough carbon dioxide (sometimes caused by hyperventilation)

The normal blood pH is tightly regulated between 7.35 and 7.45.

Carbon monoxide:   hemoglobin has a higher affinity for CO than for O2 how would CO affect internal and external respiration?


Monday 3 April 2023

Presentations

 

Choose one of the following assignments to do, & present to the class:

1.  Read this article and make a poster, powerpoint or cartoon to summarize the main points 

2.  Make a  powerpoint presentation of K2   Find out what foods have these vitamins and what happens during a deficiency.  What cultures have foods that contain vitamin K2. Tell us about how K2 improves bone health.  Include examples such as Natto, or Gouda or another example of food that contains K2

3.  Nixtamalization is a process where maize is soaked in an alkaline solution to help increase the bioavailability of niacin, an essential vitamin for energy reactions.  What cultures practice nixtamalization and what steps were needed to make it happen?

4.  Fecal transplants: This treatment is used for infection of C. difficile.  Describe the symptoms and the risk factors for C. difficile and how a fecal transplant is very effective for treating this disease.

5.  What are some examples of probiotic food and prebiotic food? These foods support a healthy microbiome.  Do some research and present your findings. 

6.  Vitamin D has many functions in your body including for bone health and immunity support.  What are the functions of Vitamin D in the body, what are the food sources and why is everyone deficient in D during the winter months, if you live in Canada? 

7.  Genus vaccinium includes huckleberry, bog cranberry and blueberry.  Investigate indigenous uses of these berries and identify the nutrients that come from these foods

8.  Vitamin A is from marine fish oil, which is a traditional food in populations that live up north.  Investigate the uses of vitamin A in the body and give a presentation on a case study of a population that eats cold water fish or takes fish oil, including codliver oil 




Monday 27 March 2023

Notes on Digestion: Complete a cartoon of digestion using the diagrams

 Here are your digestion notes

You will go through the textbook and take notes on Digestion.  Fill in the diagrams provided with the materials in the text.  

Today we looked at whether a donut hole is on the outside or the inside of a donut and we took notes on how human body systems are made of cells with a self cell marker known as a major histocompatibility complex. This complex forms a cellular identification which helps the immune system recognize it and avoid attacking those self cells.  Foreign proteins are called ANTIGENS.  

The Digestive System has the following functions:

1. DIGESTION

2. ABSORPTION

3. ELIMINATION 

4.  MICROBIOME


 DIGESTION

- mechanical digestion: USING TEETH in the mouth or PERISTALSIS in the stomach

-chemical digestion USING ENZYMES in the mouth, stomach and duodenum

ABSORPTION

- amino acids, monosaccharides, nucleic acids and lipids are absorbed in the small intestines

- water and vitamins are absorbed in the large intestines

ELIMINATION

-rectum stores undigested food

- anus eliminates undigested food 


MICROBIOME

- microbes live on the skin and also the gastro intestinal tract.  There are more bacteria living on a human body than there are cells on the human body.  The composition of the microbiome influences health and disease 


3 column notes assignment:

Create 3 column notes summarizing the part of the gastrointestinal tract and the details of how mechanical and chemical digestion takes place. 

LIST OF ORGANS:

Mouth, salivary gland , pharynx, epiglottis, esophagus, stomach, duodenum,  liver, gall bladder, pancreas, small intestine, large intestine rectum, anus 

Some of  organs are accessory organs which produce enzymes for digestion.  Summarize what enzymes are produced, stored and write details about how this happens.  THESE are the three columns:

ORGAN and function.             MECHANICAL DIGESTION.   CHEMICAL DIGESTION 

MOUTH

is the food receiver                   chewing food                                starch     --salivary amylase--> glucose 


SALIVARY GLAND

produces salivary

amylase 


PHARYNX 

a region between the mouth and esophagus 

where swallowing happens . 

tonsils are located here


EPIGLOTTIS

a fleshy flap that prevents

food from entering trachea


ESOPHAGUS

conducts a bolus of

 food using 

peristalsis 


STOMACH

- digests proteins            MECHANICAL DIGESTION                       CHEMICAL DIGESTION

                                       food  is churned using peristalsis                  pepsinogen -->pepsin

                                                                                                        protein ---pepsin , HCL---> polypeptides

- stomach  has 

gastric pits which produce

mucous, HCL and pepsinogen


Digestion Colouring Diagram:

Colour and label what happens in each part of the digestive system 

In this assignment you were to write what happens in each organ and also include lab diagrams of the small intestine.

45-50. an excellent job summarizing what happens in each organ. It is complete, and organized, accurate and creatively done, in colour.  This stands out for its excellence

40 -45 an excellent job summarizing what happens in each organ. It is complete, and organized, accurate and creatively done, in colour.  some minor elements are missing but this is exceptionally done

30-40. This is a very good summary of each organ. it is complete, organized and beautifully done.  a few more details are necessary to describe what is happening in each section

25. This is a good start and more work needs to be done to complete it. 



Thursday 9 March 2023

Raw Liver Latte Lab. and the Milk Lab

 Today we did a lab where we used raw pork liver enzyme to speed up the rate of reaction.  Our reaction was a decomposition reaction where Hydrogen Peroxide decomposed into water and oxygen.  We used both raw liver and partially cooked liver and observed the results.  



Write up this lab as a lab report. Format may be one of the following

1. Handwritten in ink and drawings as observations

2.  Word document with photos as observations

3.  Powerpoint format (include a pdf version in case ppt does not load.  upload as a file instead of sharing a link)

You may work as a group, however, each member of the group must do a task and you must include the % that each person contributed to the entire project. this can be the last page of your report.  You may also work individually. 

LAB REPORT FORMAT

Purpose: Write the purpose of this experiment. Include the balanced equation. 

Procedure: Draw a cartoon of exactly what you did and include photos of your procedure

Observations: 

Use words and images  (drawings or photos or screengrabs of video ) to describe what happened.  hint, your video might include an image of the flame that is more dramatic than a photo. Screengrab the best image).  

Discussion:

Explain your observations.  What was the foam that was made? Why did the glowing splint ignite? Did the heated up liver make a bigger or smaller reaction? 

Conclusion: Write a conclusion summarizing what you learned about enzymes during this lab 


Evaluation:

Liver Latte Experiment: 40 marks. 

35-40.  your lab report is a brilliant and detailed summary of your experiment.  You meticulously record the procedure in a creative format that communicates exactly what was done.  Your observations show what happened, including some of the unexpected things.  Your discussion is well written and you show evidence for your explanations.  Your conclusion is a great summary of the experiment and you reference what you know about enzymes in your report.  Brilliant work. 

32-34. your lab report is an excellent detailed summary of your experiment.  You  record the procedure in a creative format that communicates exactly what was done.  Your observations show what happened, including some of the unexpected things.  Your discussion is well written and you show good reasoning for your explanations.  Your conclusion is a great summary of the experiment and you reference what you know about enzymes in your report. Excellent work

20-30 your lab report is a  detailed summary of your experiment.  Yourecord the procedure in a creative format that communicates clearly what was done.  Your observations show what happened.  Your discussion is well written but you must show a bit more evidence for your explanations.  Your conclusion is a great summary of the experiment and you reference what you know about enzymes in your report. 

0-20. This is a great start and it needs more writing to finish the work. 


MILK LAB WRITE UP /10 marks

You did a lab where you dropped food dye in milk and then you added a drop of soap.  Write a one page observation of what you found and explain how this happened using your best hypothesis. 

Include a photo. 

10 marks for completion of this. 






Wednesday 8 March 2023

News article on Ventilation

 Read this news article on ventilation in public places :

https://www.nature.com/articles/d41586-023-00642-9


  • NEWS FEATURE

Indoor air is full of flu and COVID viruses. Will countries clean it up?



Monday 27 February 2023

Analyzing Breakfast for Macromolecules & Micromolecules

 Make a lab report on your observation of a breakfast.  

Title: Analyzing Breakfast for Macromolecules

Purpose: To observe the preparation of a breakfast and identify the macromolecules and micromolecules involved. 

Method:

1. Observe a person preparing breakfast.  

2. Take photos of the preparation process (take photos of hands and ingredients, if the chef has not granted photo permission of their face).  Ask questions of the chef, and stay safe during the cooking lab.

3. Write a summary of the preparation process under the photos . Analyze the ingredients for being a polymer or monomer and identify which one.  For example, are you looking at a carbohydrate, a lipid, a protein?  What kind of carbohydrates are used in the ingredients?  Draw the molecular structure of the polymer or monomer.  For example, if there are dairy products, we are likely to see a disaccharide that is in ALL milk products. Is it a saturated or unsaturated fat that is used?  Saturated fats are often solid at room temperature and they are liquid at higher cooking temperatures.  Are cations and anions used - is there salt? What salt is used?  

4.  Hollandaise sauce is an EMULSION which uses an emulsifier.  Where is the emulsifier located? What is the process for making this special sauce and why is it so tricky?   I will take the time to explain what an emulsifier is later,  in detail,  so you can write this report.  

5.  When an egg is cooked, the proteins denature When does this denaturing take place?  I will take the time to explain the concept of proteins, amino acids and denaturing later so you may write this report. 

6.  Thank your chefs!  

Conclusion: Write what you learned from this observation. 

Due date: to be announced! 

Friday 24 February 2023

Notes on BIOCHEMISTRY

We went over the handouts which included the following concepts today

BONDS in biology

1. Ionic bond 

2. covalent

a. polar covalent - example: a water molecule

b. nonpolar covalent - example - a hydrocarbon chain

c. We learned that water  forms polar covalent bonds 


3.  Functional groups like

a. carboxyl

b. amino

c. sulfhydryl

d. ketone

e. phosphate

f. aldehyde

g. hydroxyl 


We looked at FAT facts:  

FAT is NONPOLAR and HYDROPHOBIC

There are 5 functions of fats: 

1. Energy stores

2. Insulation under the skin

3.  fat packing for organs

4.  part of the phospholipid bilayer in a cell membrane 

5. steroid hormones such as ESTROGEN and TESTOSTERONE

FATTY ACIDS are composed of a carboxyl group attached to a hydrocarbon chain.  They can be SATURATED or UNSATURATED.

UNSATURATED fats have DOUBLE BONDS which are either CIS or TRANS

When you add 3 fatty acids to a glycerol, you can make a TRIGYLCERIDE using dehydration synthesis


Wednesday 22 February 2023

Biomolecules Notes

Your teacher will review the  lecture on biomolecules here:  Please review the notes on Carbohydrates and Proteins

Biomolecules Notes 

Thursday 16 February 2023

Scenarios

 1.  An athlete forgot their water bottle when going to soccer practice.  After a while, the athlete notices that their pee is bright yellow, they are feeling light headed and dizzy.  What can they do to fix their situation and explain how their situation can be fixed by paying attention to OSMOSIS, DIFFUSION, ELECTROLYTES,  

2.  A 2 year old child is constantly getting respiratory infections, bronchitis, and lots of phlegm. They have symptoms of shortness of breath.  They say" my skin tastes REALLY SALTY!!!" What might be troubling this child.  Hint: it has something to do with carrier proteins on a cell membrane and the central dogma.  

3.   An adult wears contact lenses and decides to use distilled water instead of saline solution for cleaning their lenses.  They find that this causes great discomfort.  What might be causing their discomfort. Explain using the terms hypertonic, hypotonic, isotonic. 


Please answer these questions with a partner.  If you DRAW A PICTURE, then it communicates your answer even more effectively!  Answer in one  or two pages. Hand in before the period ends 



Tuesday 14 February 2023

Pandemic architecture to respond to infectious respiratory diseases


We will be meeting at 9:30 at the box office of the Vancouver Orpheum Theatre on March 2 for attendance to listen to a performance of Beethoven and Prokofiev.  During the performance we will take data including estimating capacity, calculating ventilation and observing design features which support displacement ventilation.  

Read this article on the history of the Orpheum Theatre




 

Happy Valentines Day!

 On this valentine's day, give YOURSELF a valentine by taking care of your heart!  


Tuesday 7 February 2023

Notes on The Cell

 On the first day of class we looked at the criteria of living things and we began to go over the Cell Structures   You will get an online quiz on wherever we get to by Thursday


THERE ARE TWO TYPES OF TRANSPORT IN A CELL

ACTIVE TRANSPORT 

    -anything that requires ATP is active transport 

    -endocytosis, which includes :

    1. Phagocytosis - a cell engulfs a smaller item using pseudopods

    2. pinocytosis

    3. receptor mediated endocytosis

Any movement of molecules AGAINST THE CONCENTRATION GRADIENT is 

active transport.  Carrier proteins are often used for Na+,  Cl+ 

           

PASSIVE TRANSPORT

    moves molecules across the plasma membrane (aka the cell membrane) ALONG

    the concentration gradient. 

    EXAMPLES:

    SIMPLE DIFFUSION - small nonpolar molecules, including O2 and CO2

    FACILITATED DIFFUSION - LARGER molecules like glucose, starch, water

     facilitated diffusion uses channel proteins , can sometimes use carrier proteins 

    

OSMOSIS 

the diffusion of water 

When an animal cell is in a hypotonic solution, it fills with water and bursts (lysis). 

A plant cell is prevented from bursting by the cell wall. A plant cell merely experiences

TURGOR PRESSURE