NOTES: a summary of what we learned about protein synthesis
A diagram worksheet summaryHuman blood smear can have the following types of blood:
a red blood cell is an erythrocyte. This erythrocyte may exhibit the antigens
A, B or Rh factor. A neutrophil and a monocyte are types of white blood cell that can "eat" foreign microbes. A platelet is a blood protein that is used for clotting blood. Have a look at this site to see more blood cells
Although you studied mitosis and meiosis in the past, it is worth a look again to make sure you have all the steps down correctly. It will help you to understand our next unit which is Genetics. This video explains how alleles are connected to the steps of mitosis and meiosis. I also assume this is familiar from last year.
Your teacher will review these steps, explaining some of the complex parts and give you time to answer the questions. Next, your teacher will review the answers to the questions. After this you will do a creative assignment to demonstrate that you understand this material.
Please watch this video1. Alaskan Serum relay of 1925, the story of Togo and Balto
2. Influenza: H3N2 subclade K flu, Avian Flu H5N1
3. TB
4. Measles
5. Meat allergy alpha gal case
6. HPV and cervical cancer
7. Mpox clade 1 &2
8. Tetanus ER protocols and the story of the boy in 2017 in Oregon who was not immunized against Tetanus
9. Meningitis B in Nova Scotia: The story of Kai
We reviewed the immune system in class.
1. The immune system can be divided into SPECIFIC responses and NONSPECIFIC responses.
a. What are the two kinds of specific responses and what cells are involved?
b. What are the two kinds of nonspecific responses?
2. For barriers, describe the kinds of barriers that are in the
a. respiratory system
b. digestive system
c. reproductive system
d. skin
3. The inflammatory response happens when there is a break in the barrier. List all the steps of the inflammation response, including all the cells that are involved and the cell communication that takes place.
4. Is inflammation LOCAL , happening in a specific place, or is it SYSTEMIC, happening all over the body?
5. Describe the following cases where the inflammatory response is not working properly. What is the cause, the symptoms and the treatment?
a. allergy to a food item
b. sepsis
6. What are the two kinds of SPECIFIC IMMUNITY and what cells are involved ?
7. What is a major histocompatibility complex and how does it help protect the body?
8. Describe the steps of the humeral response.
9. describe the steps of the cell mediated response.
10 How does a T-cell get trained to do its job properly and to not attack the body?
11. Give some examples of "autoimmune" diseases.
Click on the picture below to play the video

The Major Blood Vessels. DIAGRAM
Have a look at the gross anatomy of the mammalian heart
You will receive your heart and orient it with the ventral face up and dorsal face down. Review the
Today we will introduce you to the Circulation System.
You have some fill in notes
ADVANCED LEARNING: ACTION POTENTIAL AND VECTORS:
If you are interested in a more advanced understanding of the cardiac conduction system, this website is an excellent source that goes into detail on resting potential and action potential in myocytes. Here is a very advanced tutorial on electrical vectors of the heart
update:
patient bloodwork is available here and their ECG results are here for the bloodwork, the first number is the patient's result. The second number is the normal range and the third column shows units
You may approach the patients during FIT time and some , not all are available during our class time. Many are not available during lunch. You have until the end of the week to solve this problem.
Disease Activity 2025 STUDENT HANDOUT
The powerpoint introducing this activity is on TEAMS
Name/s _______________________________________________________ block ______________________
Patient HISTORY :
WHAT IS THE NAME OF YOUR PATIENT? WHAT IS THEIR BACKGROUND? TELL ME SOME THINGS ABOUT THEM THAT ARE NOT MENTIONED IN THE BIOGRAPHIES
patient Symptoms
1. Observe any physical and emotional symptoms of your patient. What are the symptoms that you observe? Are they experiencing discomfort or pain anywhere? Do they have pain in the belly or the head etc?
2. Ask your patients some questions and record their responses . Examples of questions:
Do they have any of these symptoms: fever, chills, shortness of breath, nausea, headache, chest pain, runny nose, cough, productive cough? (with phlegm) . Do they have a sense of fullness, pain anywhere in the head, ear, throat? Have they ever been exposed to people who are sick? Do they have, contact with environmental pollution like coal dust, asbestos or any other substance? . Do they smoke? What is their overall mood? Do they have any gastrointestinal symptoms? Ask if they have been swabbed for bacterial infection.
https://depts.washington.edu/physdx/pulmonary/tech.html
Do they have any copies of their imaging such as an X-ray?
Their bloodwork and any other test results will be given to you at a later time.
7. Would you suggest that this patient follow up with a medical doctor? Why or why not? What tests do you think their doctor will order to confirm your hypothesis.
ASSIGNMENT. 72 marks total
Answer all the questions and write a report due at the end of the activity . Your report must show that yoi use EVIDENCE TO COME TO YOUR CONCLUSIONS and you communicate that evidence clearly out of 60 marks
You can also post pictures of interviewing patients on the class observation site with the full names of your group. Remember to ask before taking a picture of anyone
You managed to interview and write observations on all 12 patients out of 12 marks.
Make some 2 column notes on the following resources. I will be adding to these resources as time goes by.
READ ABOUT these Lung Diseases
as well as ones that are listed by the Canadian Lung association
Read about how health care workers examine lung sounds :
https://depts.washington.edu/physdx/pulmonary/tech.html
Have a look at Radiology samples:
Normal chest x-ray
https://radiologyassistant.nl/chest/chest-x-ray/basic-interpretation
Chest x-rays that show diseases
https://radiologyassistant.nl/chest/chest-x-ray/lung-disease
CARBAMINOHEMOGLOBIN!
Draw and label the low and medium power and draw a circle by using a petri dish to draw the circle.
In the image below, the villi are shown as finger like projections. The cells on the villi have microvilli but these are very difficult to see.
Here are your digestion notes
More detailed notes for your reading
You will go through the textbook and take notes on Digestion. Fill in the diagrams provided with the materials in the text.
Today we looked at whether a donut hole is on the outside or the inside of a donut and we took notes on how human body systems are made of cells with a self cell marker known as a major histocompatibility complex. This complex forms a cellular identification which helps the immune system recognize it and avoid attacking those self cells. Foreign proteins are called ANTIGENS.
The Digestive System has the following functions:
1. DIGESTION
2. ABSORPTION
3. ELIMINATION
4. MICROBIOME
DIGESTION
- mechanical digestion: USING TEETH in the mouth or PERISTALSIS in the stomach
-chemical digestion USING ENZYMES in the mouth, stomach and duodenum
ABSORPTION
- amino acids, monosaccharides, nucleic acids and lipids are absorbed in the small intestines
- water and vitamins are absorbed in the large intestines
ELIMINATION
-rectum stores undigested food
- anus eliminates undigested food
MICROBIOME
- microbes live on the skin and also the gastro intestinal tract. There are more bacteria living on a human body than there are cells on the human body. The composition of the microbiome influences health and disease
3 column notes assignment:
Create 3 column notes summarizing the part of the gastrointestinal tract and the details of how mechanical and chemical digestion takes place.
LIST OF ORGANS:
Mouth, salivary gland , pharynx, epiglottis, esophagus, stomach, duodenum, liver, gall bladder, pancreas, small intestine, large intestine rectum, anus
Some of organs are accessory organs which produce enzymes for digestion. Summarize what enzymes are produced, stored and write details about how this happens. THESE are the three columns:
ORGAN and function. MECHANICAL DIGESTION. CHEMICAL DIGESTION
MOUTH
is the food receiver chewing food starch --salivary amylase--> glucose
SALIVARY GLAND
produces salivary
amylase
PHARYNX
a region between the mouth and esophagus
where swallowing happens .
tonsils are located here
EPIGLOTTIS
a fleshy flap that prevents
food from entering trachea
ESOPHAGUS
conducts a bolus of
food using
peristalsis
STOMACH
- digests proteins MECHANICAL DIGESTION CHEMICAL DIGESTION
food is churned using peristalsis pepsinogen -->pepsin
protein ---pepsin , HCL---> polypeptides
- stomach has
gastric pits which produce
mucous, HCL and pepsinogen
DEODENUM
Digestion Colouring Diagram:
Colour and label what happens in each part of the digestive system
We used A LIVING enzyme to speed up the rate of reaction. Our reaction was a decomposition reaction where Hydrogen Peroxide decomposed into water and oxygen. We used raw liver and raw potato and observed the results .
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Write up this lab as a lab report. Format may be one of the following
1. Handwritten in ink and drawings as observations
2. Word document with photos as observations
3. Powerpoint format (include a pdf version in case ppt does not load. upload as a file instead of sharing a link)
You may work as a group, however, each member of the group must do a task and you must include the % that each person contributed to the entire project. this can be the last page of your report. You may also work individually.
LAB REPORT FORMAT
Purpose: Write the purpose of this experiment. Include the balanced equation.
Procedure: Draw a cartoon of exactly what you did and include photos of your procedure
Observations:
Use words and images (drawings or photos or screengrabs of video ) to describe what happened. hint, your video might include an image of the flame that is more dramatic than a photo. Screengrab the best image).
Discussion:
Explain your observations. What was the foam that was made? Why did the glowing splint ignite? Did the liver or potato make a bigger or smaller reaction?
Conclusion: Write a conclusion summarizing what you learned about enzymes during this lab . Which sample produced a bigger reaction, liver or potato? Why do YOU THINK there was a bigger reaction from one of the samples? Support your answer.
Evaluation:
Liver Latte Experiment: 40 marks.
35-40. your lab report is a brilliant and detailed summary of your experiment. You meticulously record the procedure in a creative format that communicates exactly what was done. Your observations show what happened, including some of the unexpected things. Your discussion is well written and you show evidence for your explanations. Your conclusion is a great summary of the experiment and you reference what you know about enzymes in your report. Brilliant work.
32-34. your lab report is an excellent detailed summary of your experiment. You record the procedure in a creative format that communicates exactly what was done. Your observations show what happened, including some of the unexpected things. Your discussion is well written and you show good reasoning for your explanations. Your conclusion is a great summary of the experiment and you reference what you know about enzymes in your report. Excellent work
20-30 your lab report is a detailed summary of your experiment. Yourecord the procedure in a creative format that communicates clearly what was done. Your observations show what happened. Your discussion is well written but you must show a bit more evidence for your explanations. Your conclusion is a great summary of the experiment and you reference what you know about enzymes in your report.
0-20. This is a great start and it needs more writing to finish the work.
simplified enzyme presentation
MORE DETAILS IN THE NOTES HERE
Study Questions
1. What are the 2 parts of metabolism and what is the role of enzymes?
2. What do enzymes do for activation energy?
3. Draw a cartoon of the dehydration synthesis and hydrolysis of a substrate.
4. Give examples of how enzymes are named
5. What is the definition of: ENZYME, SUBSTRATE, PRODUCT,ACTIVE SITE
6. What are the 3 factors that affect enzyme action?
7. How does temperature affect enzyme action? What is the optimum enzyme temperature in a human?
8. What are the symptoms of hyperthermia and hypothermia?
9. Describe the optimum pH of enzymes in a human body. Draw a graph that illustrates the pH of digestive enzymes.
10. What are the 2 kinds of enzyme inhibition? Draw a cartoon that illustrates inhibition.
11. Give examples of competetive and noncompetetive inhibbition
12. Define these words and draw a picture that includes the terms: holoenzyme, co-enzyme, allosteric site, active site
1. Know your illustration handouts: Review the multiple choice, short answer, or matching on these booklets of drawing handouts. I will give you review questions for long answer on the day before the test.
CELL STRUCTURES. Please note a typo on slide 3:
a brief summary of cell organelles
Observe a cooking demonstration and note ALL the biomolecules in the ingredients. Take photographs of the ingredient , the recipe and the outcome. Did the biomolecules undergo any changes due to changes in thermal energy? pH? What was their state ? solid or liquid ? Did anything turn into a gas?
Demonstrate your biochemical knowledge by explaining what happened to the biomolecules. Your report may be in the form of a document, pdf, powerpoint (powerpoint is preferred)
Your report includes
a Title: What was the food that was prepared?
1. A table with the following titles: ingredient, biomolecule, draw the formula
2. Steps to make the food: Describe changes in thermal energy and pH if any
3. Conclusion: write a short paragraph summarizing what you learned/tasted
Evaluation /30
27-30. This is an excellent and complete analysis of all the biomolecules, the report is organized and includes pictures, either drawings or photos. it has excellent presentation
20-25. This is a complete analysis of all the biomolecules. the report includes pictures or drawings of most biomolecules
15-20. This is a partial list of all the biomolecules. the report contains no pictures or drawings
0-15. This report is a good start but it is not complete
lecture on biomolecules here: Please review the notes on Carbohydrates and Proteins
And here are some summary notes reviewing the same content describing the monomers and polymers that can form through dehydration synthesis and hydrolysis . your teacher will review these concepts over a few days
After reading these notes, work on this worksheet on biomolecules . The answers to these questions begin on page 8 of the Biomoledules Summary Notes in the chapter called BIOCHEMISTRY AND CELL COMPOUNDS
We will spend a few days on this important topic and then you will get a test.
At the end of this unit you can do these review questions . Our test will include these questions
Review Questions and Their Answers
in addition, i mentioned in class that you ought to be able to
1. draw each kind of monomer: an amino acid, a monosaccharide, a nucleotide. Draw an example of an amino acid (glutamate)
2. draw the hydrolysis and dehydration synthesis of monomers , like amino acids making a peptide bond
3. identify different kinds of biomolecules if you see them
Memory tricks to remember hydrolysis and dehydration synthesis. I gave you new lyrics for this abba song.